It would be fine if it were a genderbend, no real issues, whether or not I would do it would boil down to the designs being something I can interpret. (My usual preference for smaller, stylized humanoids, and all that.)

I would also request that the reference for genderbend be provided, because otherwise I would have to make a design from thin air... Errr, but there's a grey area, like, if we're talking a shota that is very feminine and Basically a girl, that's like... [laughs] Well you know, it's own territory I Guess... I would draw it as is, but like 👉👌... lol... All subjective I know but just trying to give people an idea of what's chill. You walk into the room with a shota like. Pico. and I won't ask questions... lol