No worries abt it being a serious one, sometimes you gotta ask for help. I would start this the gold standard way you should start approaching every interpersonal problem like this and try to talk to her abt it first. It may be very tempting to just drop someone over the way they've been acting, especially if you think they'd be unwilling to reconsider their behavior like you've implied, but in the end it's not a healthy way to approach relationships with other people.
Tell them about how their criticisms have been particularly hurtful, and about how you didn't [perhaps couldn't] know that whatever your mistakes were in the game were mistakes when you did it, so it's not really fair to be mean to you about it.
At this point my answer to your question depends on how she responds. If she does actually apologize for her behavior and at least attempt to do better in the future, give her a chance, y'know? But if she responds in kind with the way you've described her, it may be better for you to find a way to distance yourself.
It sounds as if she might be in your tabletop game? If not just privy to the details. If she is, you should also talk to whoever runs/hosts the games about it, see if they're willing to stand up for you, privately or otherwise. If the host is unwilling to do that for you, you may want to consider finding a new group, as it is the host's responsibility to ensure everyone is enjoying themselves in a tabletop setting. If the host tells you something to the effect of get over it, find a new group. If she's the host, find a new group.
I'm sorry that you're having to deal with that kinda bs, anon. Be brave. Best of luck.